In the world of microorganisms, fungi are a pretty hardy bunch. There are generally harder to kill than bacteria and viruses. Dermatophytes, yeasts, and molds invade nails and dig themselves deep within the nail itself. Thus an already resilient organism is even further protected by layers and layers of keratin. Because of these reasons, treating onychomycoses has been difficult, historically. Even powerful oral antimycotic medications are not 100% effective. In light of this, can any over-the-counter nail fungus treatment be effective?
Fortunately there are a number of topical over-the-counter treatments that can effectively treat nail fungus infections. One over-the-counter topical onychomycosis drug that has been shown to be effective in a few clinical trials is amorolfine. Amorolfine is available without a prescription in the United Kingdom, New Zealand, and certain other countries. It is marketed under the brand name Loceryl. Amorolfine is distributed as a nail lacquer and the effective concentration is also the way in which it is sold, namely 5%. Amorolfine nail lacquer is painted on the nail, like polish, and then dries, leaving behind the drug. The drug is able to penetrate the nail and reach the site of the fungal infection. This drug penetration takes place over a week’s time.