Lamisil is the brand name of the onychomycosis drug terbinafine hydrochloride. Lamisil can kill fungus in vitro (in a dish) and is presumed to kill or inhibit fungi in the body as well (in vivo). It is believed that Lamisil inhibits the activity of an enzyme that is important for making a component of the fungal cell wall. Without this component, the fungus cannot grow and reproduce. The drug is much more potent (4,000 times or so) at inhibiting the fungal enzyme versus the human one. Lamisil is particularly useful in treating the two major dermatophytes that cause onychomycosis: Trichophyton rubrum and Trichophyton mentagrophytes.

Lamisil is unable to kill other fungi that may be involved in onychomycosis like Candida albicans. Therefore Lamisil treatment is limited to dermatophytoses of the nail. For this reason it is important for doctors to accurately diagnose the organism that is causing the onychomycosis before starting treatment.
Toenail Fungus Treatments





